Dr. Folkman's journal entry about the discovery of fumigillin

Dr. Folkman's journal entry about the discovery of fumigillin

Folkman, M. Judah

Diaries

Angiogenesis Inhibitors

In 1984, Folkman laboratory member, Dr. Donald Ingber, noticed a fungus growing in an experiment's petri dish containing endothelial cells, and it appeared that the fungus was causing the endothelial cells to retreat. Ingber conducted experiments with using the fungus and discovered that it did indeed inhibit the growth of blood vessels. They named the discovery fumigillin, and it was later used in an antiangiogenesis drug called TNP-470.

Journal entry containing Dr. Folkman's notes about the discovery of the fungus with antiangiogenic properties, 1984 November 21

Folkman, M. Judah

1984 November 21

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M. Judah Folkman papers, 1907-2012 (inclusive), 1950-2006 (bulk). H MS c365. Box 18, folder 23.

text

3 pages

English

text

DigID0004455-0004457

The M. Judah Folkman Papers were gifted to the Harvard Medical Library in the Francis A. Countway Library of Medicine by Paula Folkman, 2011-2016, and were delivered in six accessions: 2011-133; 2013-098; 2014-014; 2016-048; 2016-140; and 2016-156.