Effects of certain 19-Nor steroids on the normal human menstrual cycle

Effects of certain 19-Nor steroids on the normal human menstrual cycle

Garcia, Celso-Ramon, 1921-

Rock, John, 1890-1984

Pincus, Gregory, 1903-1967

Infertility

This is one of the first articles to publish results from the early study at the Free Hospital for Women involving 50 female participants being treated for infertility with a hormonal regimen. Rock found that using a combination of estrogen and progesterone would fool the body into thinking it was pregnant. The women, thus “rested,” would be taken off hormones; a surprising number of these patients subsequently conceived children in what was termed the “Rock Rebound.” The effects upon ovulation, i.e. preventing the ovum from being released, indicated its potential to act as a contraceptive.

First page of the article "Effects of certain 19-Nor steroids on the normal human menstrual cycle" by Celso-Ramon Garcia, Gregory Pincus, and John Rock

Garcia, Celso-Ramon, 1921-

1956

Pincus, Gregory, 1903-1967

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Clarence Gamble papers, 1920-1970s (inclusive), 1920-1966 (bulk). H MS c23. Box 195, folder 3082.

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excerpt (1 page)

English

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DigID0002399

Donated to the Harvard Medical Library in the Francis A. Countway Library of Medicine by Gamble's wife, Sarah, and the Gamble children in 1970